PHARMACEUTICAL COMPOSITION IN PARTICLE FORM

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition in particle form which contains Linaclotide having improved stability.SOLUTION: The subject can be solved by a pharmaceutical composition in particle form in which a core of the invention is coated with (1) a layer which contains a materi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	NISHIGAWARA TSUKASA, IMAI KANEHIRA, ASHIHARA KENICHI, MURO ATSUSHI, NISHIURA NOZOMI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a pharmaceutical composition in particle form which contains Linaclotide having improved stability.SOLUTION: The subject can be solved by a pharmaceutical composition in particle form in which a core of the invention is coated with (1) a layer which contains a material having a moisture-proof effect, (2) a drug layer containing Linaclotide or pharmaceutically acceptable salt thereof, or a hydrate thereof, and (3) a layer which contains a material having a moisture-proof effect. And the invention relates to a method for producing a pharmaceutical composition in particle form which comprises (1) a process of coating a core with a layer which contains a material having moisture-proof effect, (2) a process of coating the core with a drug layer which contains a Linaclotide or a pharmaceutically acceptable salt thereof or a hydrate thereof, and (3) a process of coating the core with a layer which contains a material having moisture-proof effect.