USE OF DIPEPTIDYL PEPTIDASE IV INHIBITORS

PROBLEM TO BE SOLVED: To provide pharmaceuticals for the treatment of cardiovascular diseases or damage, renal diseases or damage, heart failure, or heart failure associated diseases, without causing side effects.SOLUTION: The invention provides use of a dipeptidyl peptidase IV inhibitor (DPP-IV inh...

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Bibliographische Detailangaben
Hauptverfasser:	PRATLEY RICHARD, FOLEY JAMES E, HUGHES THOMAS EDWARD
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide pharmaceuticals for the treatment of cardiovascular diseases or damage, renal diseases or damage, heart failure, or heart failure associated diseases, without causing side effects.SOLUTION: The invention provides use of a dipeptidyl peptidase IV inhibitor (DPP-IV inhibitor), preferably, 1-{2-[(5-cyanopyridin-2-yl)amino]ethylamino}acetyl-2(S)-cyano-pyrrolidine dihydrochloride, (S)-1-[(3-hydroxy-1-adamantyl)amino]acetyl-2-cyano-pyrrolidine, L-threo-isoleucyl thiazolidine (P32/98), MK-0431, GSK23A, BMS-477118, etc.