NOVEL HISTONE DEACETYLASE INHIBITOR

PROBLEM TO BE SOLVED: To provide a compound that can inhibit histone deacetylase (HDAC) and is suitable as a therapeutic agent for diseases associated with cell proliferation such as malignant tumors.SOLUTION: This invention provides a novel stilbene-like compound such as N-(2-aminophenyl)-4-((3-(3,...

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Bibliographische Detailangaben
Hauptverfasser:	ABDUL RAHEEM KEERI, BALAJI RAMACHANDRAN, SRIRAM RAJAGOPAL, KAMARAJ MANI, SRIDHARAN RAJAGOPAL, VIRENDRA KACHHADIA, THANASEKARAN PONPANDIAN, PRAVEEN RAJENDRAN, SURESH RATHINASAMY, UMAMAHESWARI MANI, PUNTHALIR NARAYANASWAMY
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a compound that can inhibit histone deacetylase (HDAC) and is suitable as a therapeutic agent for diseases associated with cell proliferation such as malignant tumors.SOLUTION: This invention provides a novel stilbene-like compound such as N-(2-aminophenyl)-4-((3-(3,4-difluorophenyl)-2-(4-fluorophenyl)acrylamide)methyl)benzamide, and N-(2-aminophenyl)-4-((3-(4-methoxyphenyl)-2-(phenyl)acrylamide)methyl)benzamide.