BIOCOMPATIBLE MATERIAL FOR MAMMALIAN STEM CELL GROWTH AND DIFFERENTIATION

PROBLEM TO BE SOLVED: To provide a cell or a tissue culture surface and/or a device for use in surgical/therapeutic treatment.SOLUTION: At least a part of a surface of a biocompatible material is characterized by a micro or nano-meter scale topographical structure comprising a plurality of features....

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Bibliographische Detailangaben
Hauptverfasser: ERNST MARTIN FUCHTBAUER, MORTEN FOSS, MONGENS RYTTERGARD DUCH, FINN SKOU PEDERSEN, FLEMMING BESENBACHER, JETTE LOVMAND, ANNETTE CHRISTINE FUCHTBAUER, LOTTE MARKERT
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a cell or a tissue culture surface and/or a device for use in surgical/therapeutic treatment.SOLUTION: At least a part of a surface of a biocompatible material is characterized by a micro or nano-meter scale topographical structure comprising a plurality of features. The structure comprises a biosurface structure array (BSSA) wafer 1 composed of the biocompatible material which is selected to promote the growth of undifferentiated pluripotent stem cells or serve to promote the uniform differentiated growth of stem cells. Further, the biocompatible material has a surface structure and a composition that affect a cellular function, in particular cellular functions related to gene induction, cell differentiation and the formation of bone tissue in vivo and ex-vivo.