COMPOSITION FOR MUCOSA

PROBLEM TO BE SOLVED: To provide a composition for mucosa where stability of the lipid-soluble active ingredient is maintained and also the appearance of the composition for mucosa is uniformed, adsorption of a lipid-soluble active ingredient into a mucosa such as cornea, conjunctiva, nasal mucous a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MIYAKE MIYUKI, ARITA ATSUYA, SASAKI KANA, KIKUCHI MAIKO, OKUMURA TAKASHI, ISHII REIKO, SASAKI HIDENORI, HATTORI MANABU
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To provide a composition for mucosa where stability of the lipid-soluble active ingredient is maintained and also the appearance of the composition for mucosa is uniformed, adsorption of a lipid-soluble active ingredient into a mucosa such as cornea, conjunctiva, nasal mucous and oral cavity throat is enhanced and the effect is more exerted, as the lipid-soluble active ingredient is compounded with the composition for mucosa.SOLUTION: A composition for mucosa contains (A) 0.001 to 1.0 W/V% of a lipid-soluble active ingredient and (B) a nonionic surfactant selected from polyoxyethylene polyoxypropylene copolymers where the mass ratio presented by (A):(B) is 1:0.4 to 24.0; and comprises lipid-soluble active ingredient-containing nanoemulsion particles which are obtained by adding an oil phase comprising the components (A) and (B) to an aqueous phase at 75 to 90°C followed by stirring and have the components (A) and (B) as constitutional components.