PERFUSED ORGAN HEMOSTASIS

PROBLEM TO BE SOLVED: To provide compositions, methods and kits which produce a completely bloodless surgical field, and allow speedy resection.SOLUTION: Disclosed are compositions, methods and kits to control bleeding through the use of an internal occlusion agent based on polymer solutions, includ...

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Hauptverfasser: PETER N MADRAS, JEAN-MARIE VOGEL, JAMES A WILKIE
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide compositions, methods and kits which produce a completely bloodless surgical field, and allow speedy resection.SOLUTION: Disclosed are compositions, methods and kits to control bleeding through the use of an internal occlusion agent based on polymer solutions, including use of reverse thermosensitive polymers in nephron-sparing surgeries. In certain embodiments, after a certain amount of time, the blood flow gradually resumes, with no apparent adverse effect on the kidney. In certain embodiments, restoration of blood flow may be accelerated by cooling the kidney. The compositions, methods and kits for perfused organ hemostasis can also be used to simplify or to enable other organ surgeries or interventional procedures, including liver surgery, prostate surgery, brain surgery, surgery of the uterus, spleen surgery and any surgery on any highly vascularized organs.