2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVE AS VIIA FACTOR INHIBITOR

2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVE AS VIIA FACTOR INHIBITOR

PROBLEM TO BE SOLVED: To provide a method for treating and preventing thrombo-embolic diseases, cancers or rheumatoid arthritis.SOLUTION: The compound is a new inhibitor of serine proteases VIIa-factor, IXa-factor, Xa-factor, Xia-factor, particularly VIIa-factor found in circulation, for treating/pr...

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Bibliographische Detailangaben
Hauptverfasser: KOLESNIKOV ALEKSANDR, TORKELSON STEVEN M, YOUNG WENDY B, RAI ROOPA, SHRADER WILLIAM DVORAK, WESSON KIERON E
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a method for treating and preventing thrombo-embolic diseases, cancers or rheumatoid arthritis.SOLUTION: The compound is a new inhibitor of serine proteases VIIa-factor, IXa-factor, Xa-factor, Xia-factor, particularly VIIa-factor found in circulation, for treating/preventing a thrombosis coagulation-inducing event. A pharmaceutical composition comprises this inhibitor and a method uses these inhibitors. Further, a method is for preparation of these inhibitors.