[F-18]-LABELED L-GLUTAMIC ACID, [F-18]-LABELED L-GLUTAMINE, DERIVATIVE THEREOF, AND USE AND METHOD THEREOF FOR PREPARATION THEREOF

PROBLEM TO BE SOLVED: To provide a diagnostic agent for positron emission tomography, comprising a [F-18]-labeled compound.SOLUTION: A diagnostic agent for positron emission tomography (PET) comprises a compound which is a L-glutamic acid or L-glutamic acid derivative labeled with F-18, represented...

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Hauptverfasser: KUZNETSOVA OLGA FEDOROVNA, KEITH GRAHAM, FRIEBE MATTHIAS, LUDGER DINKELBORG, YURI BELOKON, MATHIAS BERNDT, LEHMANN LUTZ, HERIBERT SCHMITT-WILLICH, KRASIKOWA RAISA NIKOLAEVNA
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a diagnostic agent for positron emission tomography, comprising a [F-18]-labeled compound.SOLUTION: A diagnostic agent for positron emission tomography (PET) comprises a compound which is a L-glutamic acid or L-glutamic acid derivative labeled with F-18, represented by the formula (I). [In the formula, A represents hydroxyl, NH2 or O-Z; G represents hydroxyl or O-Z, Rand Rrepresent hydrogen orF, where any one of the substituents Ror RisF isotope and the other substituent is hydrogen; and Z represents a metal cation.]