AMPHOTERICIN B-CONTAINING COMPOSITION, AND PRODUCTION METHOD THEREOF

PROBLEM TO BE SOLVED: To provide a water-soluble solid composition and an aqueous composition which contain amphotericin B, and to provide a production method thereof.SOLUTION: A solid composition containing amphotericin B and polyethylene glycol monostearate is obtained by steps of: (i) dissolving...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	TSUBOI TAKASHI, KUWANO MITSUAKI, IBUKI HAJIME, YOSHII KENTA
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a water-soluble solid composition and an aqueous composition which contain amphotericin B, and to provide a production method thereof.SOLUTION: A solid composition containing amphotericin B and polyethylene glycol monostearate is obtained by steps of: (i) dissolving the amphotericin B in a lower alcohol and then distilling the lower alcohol out, followed by adding the polyethylene glycol monostearate; or (ii) dissolving the amphotericin B and the polyethylene glycol monostearate in a lower alcohol and then distilling the lower alcohol out. An aqueous composition is obtained by adding water to the solid composition.