COMPOSITIONS, DEVICES, SYSTEMS, AND METHODS FOR USING NANOPORE

PROBLEM TO BE SOLVED: To provide devices and methods that can detect and control an individual polymer in a mixture to be acted upon by another compound, such as an enzyme, in a nanopore.SOLUTION: The devices and methods are also used to quickly (greater than about 50 Hz) determine the nucleotide ba...

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Bibliographische Detailangaben
Hauptverfasser:	BRANTON DANIEL, KATE LIEBERMAN, WILSON NOAH A, CHEN ROGER JINTEH ARRIGO, NICHOLAS HURT, ABU-SHUMAYS ROBIN, AKESON MARK A, DAVID W DEAMER, WILLIAM B DUNBAR, SEICO BENNER
Format:	Patent
Sprache:	eng
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY APPARATUS THEREFOR BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ELECTROLYTIC OR ELECTROPHORETIC PROCESSES ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTIONOF COMPOUNDS OR NON-METALS ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide devices and methods that can detect and control an individual polymer in a mixture to be acted upon by another compound, such as an enzyme, in a nanopore.SOLUTION: The devices and methods are also used to quickly (greater than about 50 Hz) determine the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.