METHOD AND COMPOSITION TO GENERATE DNA PROBES HAVING UNIQUE SEQUENCE, LABELING OF DNA PROBES AND USE OF THE PROBES

PROBLEM TO BE SOLVED: To provide a method and a composition to obtain DNA probes having a unique sequence, in the field of identification of DNA sequences, genes or chromosomes.SOLUTION: A composition comprises any double stranded DNA containing a unique sequence from which repetitive sequences are...

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Bibliographische Detailangaben
Hauptverfasser: CONNELLY MARK CARLE, SWENNENHUIS JOOST F, TIBBE ARJAN G J, VERRANT JOHN A, FOULK BRAD, KAGAN MICHAEL T, TERSTAPPEN LEON W M M
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a method and a composition to obtain DNA probes having a unique sequence, in the field of identification of DNA sequences, genes or chromosomes.SOLUTION: A composition comprises any double stranded DNA containing a unique sequence from which repetitive sequences are eliminated according to the method described in this invention. The invention relates to preservation of cells that are identified after immunomagnetic selection and fluorescent labeling, in order to further investigate the cells of interest. The invention also relates to genetic analysis of cells that are identified after immunomagnetic selection and fluorescent labeling.