ANTI-KIR ANTIBODIES, FORMULATIONS, AND USES THEREOF

PROBLEM TO BE SOLVED: To provide: novel antibodies against specific killer immunoglobulin-like receptors (KIRs); formulations, dosages, and administration schedules for these and/or other therapeutic anti-KIR antibodies; and methods of producing and using the same.SOLUTION: The present invention pro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SVENDSEN IVAN, ROZANA SVENDSEN, PETER ANDREAS NICOLAI REUMERT WAGTMANN, RUNE VIIG OVERGAARD, LENE-HJORTH ALIFRANGIS
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To provide: novel antibodies against specific killer immunoglobulin-like receptors (KIRs); formulations, dosages, and administration schedules for these and/or other therapeutic anti-KIR antibodies; and methods of producing and using the same.SOLUTION: The present invention provides: a novel IgG4 isotype anti-KIR antibody; novel formulations of other IgG4 anti-KIR antibodies; compositions, formulations, dosages, and administration regimens suitable for NK cell activation; therapeutic applications of anti-KIR antibodies; and kits comprising one or more anti-KIR antibodies with instructions for use in treating cancer.