NOVEL AURKC FUSION

PROBLEM TO BE SOLVED: To provide a method for determining a polynucleotide that is a new cancer causative gene and thereby detecting the polynucleotide or a polypeptide that it encodes, and a kit and a primer set therefor.SOLUTION: A method is provided for determining that a fusion gene between part...

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Bibliographische Detailangaben
Hauptverfasser:	NISHIMURA KOICHI, ASAMI MAKOTO, KADOYAMA KAZUHISA, SUZUKI ATSUSHI
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a method for determining a polynucleotide that is a new cancer causative gene and thereby detecting the polynucleotide or a polypeptide that it encodes, and a kit and a primer set therefor.SOLUTION: A method is provided for determining that a fusion gene between part of ZNF264 gene present in some cancer patients and part of AURKC gene is a cancer causative gene, and detecting a polynucleotide being the gene and a polypeptide encoded by the gene. The detection method includes detecting a fusion gene between part of ZNF264 gene and part of AURKC gene, or a fusion protein that it encodes. A primer set or a detection kit includes a sense primer designed from a portion coding ZNF264 and an antisense primer designed from a portion encoding AURKC.