STABILIZED PITAVASTATIN PREPARATION

PROBLEM TO BE SOLVED: To provide a basic pharmaceutical composition including pitavastatin having superior storage stability.SOLUTION: A pharmaceutical composition consists of pitavastatin or a salt thereof, a solvent or an ester, about 3-20 wt.% of magnesium oxide, and a pharmaceutically acceptable...

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Bibliographische Detailangaben
Hauptverfasser:	LIN CHEING, HSIAO YUIEN, CHANG CHI TAI
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a basic pharmaceutical composition including pitavastatin having superior storage stability.SOLUTION: A pharmaceutical composition consists of pitavastatin or a salt thereof, a solvent or an ester, about 3-20 wt.% of magnesium oxide, and a pharmaceutically acceptable carrier. An aqueous solution or dispersion of the pharmaceutical composition has pH of 10-10.8. The pharmaceutical composition may further include at least one material selected from the group consisting of a vehicle, a disintegrator, a binder and a lubricant. The pharmaceutical composition has superior time-dependent stability and causes no change in appearance even after storage for a long period of time.