METHOD OF PRODUCING ω-BROMOACETOACETIC ANILIDES
PROBLEM TO BE SOLVED: To provide a method of producing ω-bromoacetic anilides which can use not only halogen-based solvent, alcohol solvent or organic acid solvent but also various organic solvents and regioselectively and highly efficiently brominates acetoacetic anilides, thereby producing ω-bromo...
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Sprache: | eng |
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Zusammenfassung: | PROBLEM TO BE SOLVED: To provide a method of producing ω-bromoacetic anilides which can use not only halogen-based solvent, alcohol solvent or organic acid solvent but also various organic solvents and regioselectively and highly efficiently brominates acetoacetic anilides, thereby producing ω-bromoacetoacetic anilides, the method having a wide range of applying a base.SOLUTION: By reacting acetoacetic anilides with pyridinium bromide perbromide in an organic solvent, ω-bromoacetoacetic anilides are selectively obtained. |
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