MICROPORE-PERFORATION OF TISSUE FOR DELIVERY OF BIOACTIVE AGENT

PROBLEM TO BE SOLVED: To provide a method of enhancing the permeability of a biological membrane, including the skin or mucosa of an animal or the outer layer of a plant to a permeable substance.SOLUTION: A method of enhancing the permeability of a biological membrane, including the skin or mucosa o...

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Bibliographische Detailangaben
1. Verfasser:	EPPSTEIN JONATHAN A
Format:	Patent
Sprache:	eng
Schlagworte:	DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DIAGNOSIS ELECTROTHERAPY HUMAN NECESSITIES HYGIENE IDENTIFICATION MAGNETOTHERAPY MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES RADIATION THERAPY SURGERY ULTRASOUND THERAPY
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a method of enhancing the permeability of a biological membrane, including the skin or mucosa of an animal or the outer layer of a plant to a permeable substance.SOLUTION: A method of enhancing the permeability of a biological membrane, including the skin or mucosa of an animal or the outer layer of a plant to a permeable substance described utilizing micropore-perforation of selected depth and optionally one or more of sonic, electromagnetic, mechanical and thermal energy and a chemical enhancer. Micropore-perforation is accomplished to form a micropore of selected depth in the biological membrane and the perforated site is contacted with the permeable substance. Additional permeation enhancement measures may be applied to the site to enhance both the flux rate of the permeable substance into the organism through the micropore-perforation as well as into targeted tissues within the organism.