METHOD FOR PRODUCING AMIDE COMPOUND

PROBLEM TO BE SOLVED: To provide a reaction process which can be scaled up inexpensively and simply in a method for continuously producing a high-concentration aqueous solution of an amide compound by using a reaction vessel having a plug-flow region to hydrate a nitrile compound at a high conversio...

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Hauptverfasser:	ISHIDA TSUTOMU, SATO ARATA, WATANABE SHIGEO, ARII TERUO
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a reaction process which can be scaled up inexpensively and simply in a method for continuously producing a high-concentration aqueous solution of an amide compound by using a reaction vessel having a plug-flow region to hydrate a nitrile compound at a high conversion rate.SOLUTION: In a method for producing an amide compound, nitrile-hydratase-containing microbial cells or a processed product of the microbial cells is brought into contact with a nitrile compound in an aqueous vehicle, and the reaction solution containing the obtained amide compound is then further reacted by using a reactor that has no heat-removal equipment and has a plug-flow region.