METHOD AND MEDICINE FOR INHIBITING EXPRESSION OF SPECIFIC GENE

PROBLEM TO BE SOLVED: To provide a medicine containing at least one double-stranded oligoribonucleotide (double-stranded RNA) designed to inhibit the expression of a target gene.SOLUTION: One strand of the double-stranded RNA is at least partially complementary to a targeted gene. The targeted gene...

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Bibliographische Detailangaben
Hauptverfasser:	KREUTZER ROLAND, LIMMER STEPHAN
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a medicine containing at least one double-stranded oligoribonucleotide (double-stranded RNA) designed to inhibit the expression of a target gene.SOLUTION: One strand of the double-stranded RNA is at least partially complementary to a targeted gene. The targeted gene can be selected from the following group: cancer genes, cytokine genes, Id protein genes, developmental genes, and prion genes. The target gene can be expressed in a pathogenic organisms (especially Plasmodium). The targeted gene can preferably also be a part of viruses or viroids which are pathogenic to humans.