STABILIZED PHARMACEUTICAL COMPOSITION
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition in which the increase in impurities accompanying the preparation of benzimidazole-7-carboxylic acid represented by candesartan or candesartan cilexetil or its derivative is suppressed, and reduction with time in the contents is prevented,...
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creator | MOCHIZUKI RYOSUKE YASUI MASAMI IWANE HIDENORI |
description | PROBLEM TO BE SOLVED: To provide a pharmaceutical composition in which the increase in impurities accompanying the preparation of benzimidazole-7-carboxylic acid represented by candesartan or candesartan cilexetil or its derivative is suppressed, and reduction with time in the contents is prevented, and a method for preparing the composition.SOLUTION: The stable pharmaceutical composition can be obtained when benzimidazole-7-carboxylic acid or its derivative is blended with polyhydric alcohol. Namely, technical ethics is established that the addition of polyhydric alcohol remarkably suppresses the decomposition of effective components, suppresses the increase in impurities accompanying the preparation, and prevents the reduction with time in the contents of the effective components. |
format | Patent |
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Namely, technical ethics is established that the addition of polyhydric alcohol remarkably suppresses the decomposition of effective components, suppresses the increase in impurities accompanying the preparation, and prevents the reduction with time in the contents of the effective components.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130418&DB=EPODOC&CC=JP&NR=2013067574A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130418&DB=EPODOC&CC=JP&NR=2013067574A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MOCHIZUKI RYOSUKE</creatorcontrib><creatorcontrib>YASUI MASAMI</creatorcontrib><creatorcontrib>IWANE HIDENORI</creatorcontrib><title>STABILIZED PHARMACEUTICAL COMPOSITION</title><description>PROBLEM TO BE SOLVED: To provide a pharmaceutical composition in which the increase in impurities accompanying the preparation of benzimidazole-7-carboxylic acid represented by candesartan or candesartan cilexetil or its derivative is suppressed, and reduction with time in the contents is prevented, and a method for preparing the composition.SOLUTION: The stable pharmaceutical composition can be obtained when benzimidazole-7-carboxylic acid or its derivative is blended with polyhydric alcohol. 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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | STABILIZED PHARMACEUTICAL COMPOSITION |
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