DELIVERY SYSTEM AND METHOD USING PREFORMED BIODEGRADABLE POLYMER COMPOSITION
PROBLEM TO BE SOLVED: To provide a delivery system for delivering active agents to a subject, which can provide various biodegradation and delivery rates.SOLUTION: The delivery system uses a preformed biodegradable polymer composition represented by a formula of I-(-X-LM-G)n [wherein X is a bifuncti...
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creator | FERBER RICHARD H POURNOOR KAVEH VELASQUEZ DAVID J TRUONG MYHANH T CHOI HYE-OK BERNATCHEZ STEPHANIE F |
description | PROBLEM TO BE SOLVED: To provide a delivery system for delivering active agents to a subject, which can provide various biodegradation and delivery rates.SOLUTION: The delivery system uses a preformed biodegradable polymer composition represented by a formula of I-(-X-LM-G)n [wherein X is a bifunctional polyoxyethylene chain portion or bond ; LM is a bifunctional connecting part represented by -C(O)-, -(CH2)bC(O)- (b is an integer of 1 to 5), -C(O)-(CH)c-C(O)- (c is an integer of 2 to 10) or -C(O)-O-(CH)d-O-C(O)- (d is an integer of 2 to 10)]; G is a leaving group such as N-oxysuccinimidyl ; and I is a multifunctional connecting part induced from a multnucleophilic compound, and is a crosslinked albumin desolvated at least partially. |
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LM is a bifunctional connecting part represented by -C(O)-, -(CH2)bC(O)- (b is an integer of 1 to 5), -C(O)-(CH)c-C(O)- (c is an integer of 2 to 10) or -C(O)-O-(CH)d-O-C(O)- (d is an integer of 2 to 10)]; G is a leaving group such as N-oxysuccinimidyl ; and I is a multifunctional connecting part induced from a multnucleophilic compound, and is a crosslinked albumin desolvated at least partially.</description><language>eng</language><subject>CHEMISTRY ; COMPOSITIONS BASED THEREON ; HUMAN NECESSITIES ; HYGIENE ; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC MACROMOLECULAR COMPOUNDS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130117&DB=EPODOC&CC=JP&NR=2013010774A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130117&DB=EPODOC&CC=JP&NR=2013010774A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FERBER RICHARD H</creatorcontrib><creatorcontrib>POURNOOR KAVEH</creatorcontrib><creatorcontrib>VELASQUEZ DAVID J</creatorcontrib><creatorcontrib>TRUONG MYHANH T</creatorcontrib><creatorcontrib>CHOI HYE-OK</creatorcontrib><creatorcontrib>BERNATCHEZ STEPHANIE F</creatorcontrib><title>DELIVERY SYSTEM AND METHOD USING PREFORMED BIODEGRADABLE POLYMER COMPOSITION</title><description>PROBLEM TO BE SOLVED: To provide a delivery system for delivering active agents to a subject, which can provide various biodegradation and delivery rates.SOLUTION: The delivery system uses a preformed biodegradable polymer composition represented by a formula of I-(-X-LM-G)n [wherein X is a bifunctional polyoxyethylene chain portion or bond ; 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LM is a bifunctional connecting part represented by -C(O)-, -(CH2)bC(O)- (b is an integer of 1 to 5), -C(O)-(CH)c-C(O)- (c is an integer of 2 to 10) or -C(O)-O-(CH)d-O-C(O)- (d is an integer of 2 to 10)]; G is a leaving group such as N-oxysuccinimidyl ; and I is a multifunctional connecting part induced from a multnucleophilic compound, and is a crosslinked albumin desolvated at least partially.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP |
title | DELIVERY SYSTEM AND METHOD USING PREFORMED BIODEGRADABLE POLYMER COMPOSITION |
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