LOW DOSE ENTECAVIR FORMULATION AND USE OF THE SAME

PROBLEM TO BE SOLVED: To provide a low dose Entecavir-containing formulation capable of once daily administration for treatment of hepatitis B virus infectious disease and/or a simultaneous infection, and a method for manufacturing the same.SOLUTION: Disclosed is a pharmaceutical composition in tabl...

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Bibliographische Detailangaben
Hauptverfasser: COLONNO RICHARD J, SPROCKEL OMAR L, FAKES MICHAEL G, HARIANAWALA ABIZER, DESAI DIVYAKANT
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a low dose Entecavir-containing formulation capable of once daily administration for treatment of hepatitis B virus infectious disease and/or a simultaneous infection, and a method for manufacturing the same.SOLUTION: Disclosed is a pharmaceutical composition in tablet or capsule form containing 0.5 mg/form of Entecavir attached by povidone as an adhesive to a pharmaceutically acceptable carrier. It is all right even if any other pharmaceutically active substance is contained in the Entecavir composition, or if such a substance is dosed separately from the Entecavir composition.