MEDICINE FOR REPAIRING, REGENERATING AND TREATING INTERNAL ORGAN TISSUE BY NOVEL BENZOISOFRANONE DERIVATIVE

PROBLEM TO BE SOLVED: To provide a novel benzoisofranone derivative as a medicine which acts on a response by gamma interferon between an epithelial cell and a stroma cell to induce the repair and regeneration of an internal organ tissue after the tissue concerned is damaged; to provide a novel benz...

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Hauptverfasser:	TANAKA TETSUAKI, ISHIBASHI MICHIO, KOJIMA NAOTO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a novel benzoisofranone derivative as a medicine which acts on a response by gamma interferon between an epithelial cell and a stroma cell to induce the repair and regeneration of an internal organ tissue after the tissue concerned is damaged; to provide a novel benzoisofranone derivative as a medicine which acts on a response by lymphotoxin alpha between an epithelial cell and a stroma cell to induce the repair and regeneration of an internal organ tissue after the tissue concerned is damaged; and to provide a novel benzoisofranone derivative as a medicine which modifies a responsive reaction in a process, in which a cell is damaged by TGF-beta 1, to induce the repair and regeneration of an internal organ tissue after the tissue concerned is damaged.SOLUTION: The novel benzoisofranone derivative, which has the action to modify a process in which a cell is damaged, is a medicine for repairing, regenerating and treating an internal organ tissue. The novel benzoisofranone derivative; which has the action to modify a process in which a cell is damaged, together with a macrophage or a tissue-effector cell, is a medicine for repairing, regenerating and treating an internal organ tissue.