EYE DROP FOR TREATING CONJUNCTIVITIS CONTAINING LEVOFLOXACIN, SALT THEREOF OR THEIR SOLVATE
PROBLEM TO BE SOLVED: To provide levofloxacin eye drops used in a novel method/dosage for healing an eye infection within a shorter period of time than a conventional method/dosage for preventing occurrence of resistant bacteria without increasing an incidence rate of side effects.SOLUTION: In the n...
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Zusammenfassung: | PROBLEM TO BE SOLVED: To provide levofloxacin eye drops used in a novel method/dosage for healing an eye infection within a shorter period of time than a conventional method/dosage for preventing occurrence of resistant bacteria without increasing an incidence rate of side effects.SOLUTION: In the novel method and dosage of eye drops containing 1.5% (w/v) of levofloxacin, the eye drops are dropped into the eyes thrice a day. In this way, bacterial conjunctivitis can be healed within a shorter period of time, compared with the conventional case where 0.5% (w/v) eye drops are used thrice a day, without increasing the incidence rate of side effects. Healing of an eye infection within a short period of time contributes to shortening of the exposure time of a pathogenic bacterium causing the eye infection to levofloxacin. As a result, it is expected that the novel method and dosage of levofloxacin-containing eye drops inhibit the emergence of a resistant strain caused by the prolonged usage of levofloxacin-containing eye drops in the conventional method/dosage. Moreover, it is confirmed that the novel method and dosage of levofloxacin-containing eye drops directly inhibit tolerization, which is caused by the short-term usage of levofloxacin-containing eye drops in the conventional method/dosage, in pathogenic bacteria causative of eye infections such as Staphylococcus aureus. |
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