METHOD OF PRODUCING 3-HALOALKYL-2-HYDROXYPYRAZINE DERIVATIVE

METHOD OF PRODUCING 3-HALOALKYL-2-HYDROXYPYRAZINE DERIVATIVE

PROBLEM TO BE SOLVED: To provide an industrially advantageous method of producing a 3-haloalkyl-2-hydroxypyrazine derivative useful as an intermediate for pharmaceuticals, agrochemicals and the like.SOLUTION: The method of producing a hydroxypyrazine derivative represented by formula (1) (in the for...

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Bibliographische Detailangaben
Hauptverfasser: SAWADA NAOKI, MATSUZAKI YOSHIHIRO, KAWAGUCHI MICHIHIKO
Format: Patent
Sprache:eng
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide an industrially advantageous method of producing a 3-haloalkyl-2-hydroxypyrazine derivative useful as an intermediate for pharmaceuticals, agrochemicals and the like.SOLUTION: The method of producing a hydroxypyrazine derivative represented by formula (1) (in the formula Rrepresents a 1-6C haloalkyl group) comprises allowing a dihydropyrazinone derivative represented by formula (2) (in the formula Ris the same as defined above) to react with an oxidizing agent in the presence or absence of an acid.