USE OF GELSOLINE FOR THERAPIES OF MULTIPLE SCLEROSIS AND DIAGNOSIS OF NEUROLOGIC DISEASES

PROBLEM TO BE SOLVED: To provide use of gelsoline for therapies of neurologic diseases such as multiple sclerosis, and use of gelsoline for diagnosis and observation of neurologic diseases and evaluation of therapies of neurologic diseases.SOLUTION: A method to characterize a risk profile of develop...

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Bibliographische Detailangaben
Hauptverfasser:	PO-SHUN LEE, DITTEL BONNIE, KATARZYNA MARESZ, THOMAS P STOSEL
Format:	Patent
Sprache:	eng
Schlagworte:	GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE TESTING
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide use of gelsoline for therapies of neurologic diseases such as multiple sclerosis, and use of gelsoline for diagnosis and observation of neurologic diseases and evaluation of therapies of neurologic diseases.SOLUTION: A method to characterize a risk profile of developing neurologic diseases of a subject in the future includes obtaining a gelsoline level of the subject, comparing the gelsoline level with a predetermined value, and characterizing the risk profile of developing a neurologic disease of the subject based on the gelsoline level compared to the predetermined value. A gelsoline level equal to or lower than the predetermined level indicates that the subject has a high risk of developing the neurologic disease, while a gelsoline level equal to or higher than the predetermined level indicates that the subject does not have a high risk of developing the neurologic disease.