CYANOPYRROLE AS PROGESTERONE RECEPTOR AGONIST

PROBLEM TO BE SOLVED: To provide a novel cyanopyrrole deriative and a use thereof.SOLUTION: This invention provides the cyanopyrrole deriative or pharmaceutically acceptable salt thereof which can bind to a progesterone receptor of formula 1. The compound treats or inhibits breast cancer, uterus can...

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Bibliographische Detailangaben
Hauptverfasser:	EDWARDS JAMES P, ZHI LIN, JONES TODD K, MACKNER VALERIE A, WROBEL JAY E, COLLINS MARK A, TEGLEY CHRISTOPHER M
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a novel cyanopyrrole deriative and a use thereof.SOLUTION: This invention provides the cyanopyrrole deriative or pharmaceutically acceptable salt thereof which can bind to a progesterone receptor of formula 1. The compound treats or inhibits breast cancer, uterus cancer, ovarian cancer, endometrium cancer, or prostate cancer. In the formula 1, T is O, S, or absent; and Rto Rare each, independently, hydrogen, alkyl, substituted alkyl, etc.