COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASE AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENT

PROBLEM TO BE SOLVED: To provide a method for promoting remyelination of nerve cells in a mammal including administering to the mammal a remyelination agent in a remyelinating effective amount for the treatment of a demyelinating disease such as multiple sclerosis.SOLUTION: The invention relates to a use of the remyelinating agent for the preparation of a medicament in an amount to promote remyelination of nerve cells in the mammal. The remyelinating agent is preferably an antibody, an immunologically active fragment of an antibody, especially a monoclonal antibody or an immunologically active fragment of a monoclonal antibody. The monoclonal antibody is preferably a chimeric antibody, a human antibody, a genetically engineered antibody, or a bispecific antibody. The humanized antibody is preferably a natalizumab or an immunologically active fragment of a natalizumab. The natalizumab is preferably administered intravenously or subcutaneously.