METHOD FOR PRODUCING CRYSTALLINE [R-(R,R)]-2-(4-FLUOROPHENYL)-β,δ-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1-HEPTANOIC ACID (ATORVASTATIN)

PROBLEM TO BE SOLVED: To provide a method for producing atorvastatin in a stable crystalline form which is a medicament for treating hyperlipemia and hypercholesterolemia.SOLUTION: The method for producing a crystalline form I atorvastatin or its hydrate includes (a) a step of treating an aqueous so...

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Hauptverfasser:	BRIGGS CHRISTOPHER A, HARASAWA KIKUKO, NAKAGAWA SHINSUKE, MINOHARA KAZUO, WADE ROBERT A, ICHIKAWA HAYASHI, JENNINGS REX ALLEN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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