YEAST HOST
PROBLEM TO BE SOLVED: To provide gene deficent host which is suitable for producing transformant which introduce different protein gene originated from higher animals such as human and the like. SOLUTION: An improved host is used for producing a transformant, in which mannosyl erythritol lipid (MEL)...
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Zusammenfassung: | PROBLEM TO BE SOLVED: To provide gene deficent host which is suitable for producing transformant which introduce different protein gene originated from higher animals such as human and the like. SOLUTION: An improved host is used for producing a transformant, in which mannosyl erythritol lipid (MEL) biosynthesis gene of yeast belonging to the genus Pseudozyma is deleted which has an ability to produce MEL. The improved host is suitable for expression of heterologous protein gene originated from higher animal such as humans and the like, and a transformant produced by introducing heterologous protein gene to the host is excellent in productivity of heterologous protein. COPYRIGHT: (C)2011,JPO&INPIT |
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