SUBSTRATE FOR IMMOBILIZATION OF PHYSIOLOGICALLY ACTIVE SUBSTANCE AND METHOD FOR CAPTURING PHYSIOLOGICALLY ACTIVE SUBSTANCE

PROBLEM TO BE SOLVED: To provide a substrate for immobilization for reducing nonspecific adsorption and binding and easily immobilizing physiologically active substances to a surface and to provide a method of use thereof. SOLUTION: The substrate for capturing a physiologically active substance is f...

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1. Verfasser: FUNAOKA SOHEI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a substrate for immobilization for reducing nonspecific adsorption and binding and easily immobilizing physiologically active substances to a surface and to provide a method of use thereof. SOLUTION: The substrate for capturing a physiologically active substance is formed by arranging a substrate, a resin layer, and a biotin compound in this order. The surface of the resin layer opposite to the substrate is characteristically hydrophilic. By using a solid carrier for the immobilization of physiologically active substances, it is possible to immobilize modified physiologically active substances by a biotin-binding protein and reduce the unnecessary adsorption and binding of physiologically active substances and fluorescent substances to sections other than the section of the substrate in which the modified physiologically active substances are immobilized. COPYRIGHT: (C)2011,JPO&INPIT