METHOD OF DETECTING DEGREE OF ADVERSE INFLUENCE OF MACROPHAGE ON ANIMAL
PROBLEM TO BE SOLVED: To find a marker which directly reflects negative effects of a macrophage on a patient. SOLUTION: The present invention provides a method for determining the degree of macrophage-associated negative effects on a vertebrate including a human and includes assaying diacetylpolyami...
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| creator | HAMAOKI MASARU |
| description | PROBLEM TO BE SOLVED: To find a marker which directly reflects negative effects of a macrophage on a patient. SOLUTION: The present invention provides a method for determining the degree of macrophage-associated negative effects on a vertebrate including a human and includes assaying diacetylpolyamine contained in a sample. According to the method, metabolic conditions of macrophages can be monitored, and the degree of macrophage-associated negative effects on a vertebrate including humans can be determined. More specifically, the present invention can predict, through assay of diacetylpolyamine, pathological condition which is considered a macrophage-related disease; e.g., recurrence of cancer or malignant tumor, or infiltration or activation of cancer or malignant tumor cells; denaturation or degeneration of neurons associated with Alzheimer's disease; or the onset or progression of an autoimmune disease (e.g., rheumatism or Crohn's disease) or arteriosclerosis, and thereby is very useful for clinical tests. COPYRIGHT: (C)2011,JPO&INPIT |
| format | Patent |
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SOLUTION: The present invention provides a method for determining the degree of macrophage-associated negative effects on a vertebrate including a human and includes assaying diacetylpolyamine contained in a sample. According to the method, metabolic conditions of macrophages can be monitored, and the degree of macrophage-associated negative effects on a vertebrate including humans can be determined. More specifically, the present invention can predict, through assay of diacetylpolyamine, pathological condition which is considered a macrophage-related disease; e.g., recurrence of cancer or malignant tumor, or infiltration or activation of cancer or malignant tumor cells; denaturation or degeneration of neurons associated with Alzheimer's disease; or the onset or progression of an autoimmune disease (e.g., rheumatism or Crohn's disease) or arteriosclerosis, and thereby is very useful for clinical tests. 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| subjects | GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION TECHNICAL SUBJECTS COVERED BY FORMER USPC TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TESTING |
| title | METHOD OF DETECTING DEGREE OF ADVERSE INFLUENCE OF MACROPHAGE ON ANIMAL |
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