PHARMACEUTICAL COMPOSITION OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITOR

PROBLEM TO BE SOLVED: To provide a composition including a crystalline cholesteryl ester transfer protein (CETP) inhibitor with increased biological availability. SOLUTION: The pharmaceutical composition includes the crystalline cholesteryl ester transfer protein (CETP) inhibitor and a water-insolub...

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Hauptverfasser:	SERIGAYA TAKANORI, SUNAMI MASAKI
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a composition including a crystalline cholesteryl ester transfer protein (CETP) inhibitor with increased biological availability. SOLUTION: The pharmaceutical composition includes the crystalline cholesteryl ester transfer protein (CETP) inhibitor and a water-insoluble concentration-elevating additive. The crystalline CETP may be S-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]2-methylpropanethioate and the concentration-elevating additive may use crospovidone. COPYRIGHT: (C)2011,JPO&INPIT