COMPOUND WITH 5-HT1A ACTIVITY USEFUL FOR TREATING DISORDER OF OUTER RETINA

PROBLEM TO BE SOLVED: To provide compositions and methods for treating disorders of an outer retina caused by acute or chronic ocular degenerative conditions or degenerative affections. SOLUTION: There are disclosed compositions and methods for treating disorders of the outer retina using compounds...

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Hauptverfasser: KAPIN MICHAEL A, COLLIER ROBERT J JR, HELLBERG MARK R, DEAN THOMAS R
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide compositions and methods for treating disorders of an outer retina caused by acute or chronic ocular degenerative conditions or degenerative affections. SOLUTION: There are disclosed compositions and methods for treating disorders of the outer retina using compounds with 5-HT1Aagonist activity. The invention relates to 5-HT1Aagonist useful for treating disorders of the outer retina, particularly for: AMD;RP and other forms of heredodegenerative retinal diseases; retinal detachment and tears; macular pucker; ischemia affecting the outer retina; diabetic retinopathy; damage associated with laser therapy (grid, focal and panretinal) including photodynamic therapy (PDT); trauma; surgical (retinal translocation, subretinal surgery or vitrectomy) or light-induced retinopathy; and preservation of retinal transplants. COPYRIGHT: (C)2011,JPO&INPIT