NEW THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICAL USE THEREOF

PROBLEM TO BE SOLVED: To provide a compound having glucokinase activating action.SOLUTION: A medical composition containing a compound expressed by general formula (I) (wherein X denotes a nitrogen atom or CR, Rdenotes a hydrogen atom; Rdenotes a hydrogen atom, a 1-6C alkyl group, a 1-6C alkoxy grou...

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Hauptverfasser:	CHIKAMATSU KAORI, MIYOSHI MIKA, MURAKAMI SEI, IWAI HISAKAZU, GOTO IZUMI, KASUGAI NORIYASU, YAMASHITA ATSUYUKI, OGAMI MASAKAZU, FUJIEDA HIROKI, MIYAZAWA TOSHIYUKI, SUZUKI KIMIE, KONDO YURIE, SEIFERT HANS-JUERGEN MARKUS, KATAOKA DAISUKE, MAKINO MICHIHIRO, LANG MARTIN, WOLF KAARINA KRISTINA, IDO TORU, KATO NORIYASU, TSURUTA NOBUAKI, KATAOKA HIROYO, HIRAMATSU NAOKI, SAKAIRI MASAO, WATANABE NOBUHIDE, HARADA SATOKO, TAKAHASHI NAOKI, NAGAI KAZUSHIGE
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a compound having glucokinase activating action.SOLUTION: A medical composition containing a compound expressed by general formula (I) (wherein X denotes a nitrogen atom or CR, Rdenotes a hydrogen atom; Rdenotes a hydrogen atom, a 1-6C alkyl group, a 1-6C alkoxy group or a 1-6C alkylthio group, Rdenotes a hydrogen atom or a fluorine atom; Rdenotes a hydrogen atom or a 1-6C alkyl group; and one of Rand Rdenotes a hydrogen atom or a 1-6C alkyl group, and another thereof denotes a 1-6C alkylene carboxylic acid, a 1-6C alkylsulfonyl group, 1-6C alkylcarbonyl group or CONH), a prodrug or a pharmacologically permitted salt as an active ingredient is provided.