ENTERIC SOLID ORAL DOSAGE FORM OF BISPHOSPHONATE CONTAINING CHELATING AGENT

ENTERIC SOLID ORAL DOSAGE FORM OF BISPHOSPHONATE CONTAINING CHELATING AGENT

PROBLEM TO BE SOLVED: To provide delivery of a pharmaceutical composition to the lower gastrointestinal tract of a mammal subject and pharmaceutically effective absorption of bisphosphonate with or without a food or a beverage. SOLUTION: There is provided an oral dosage form of bisphosphonate compri...

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Bibliographische Detailangaben
Hauptverfasser: BURGIO DAVID ERNEST JR, DANSEREAU RICHARD JOHN
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide delivery of a pharmaceutical composition to the lower gastrointestinal tract of a mammal subject and pharmaceutically effective absorption of bisphosphonate with or without a food or a beverage. SOLUTION: There is provided an oral dosage form of bisphosphonate comprised of a safe and effective amount of the pharmaceutical composition comprising bisphosphonate, a chelating agent, and a means for effecting delayed release of both bisphosphonate and the chelating agent in the lower gastrointestinal tract. COPYRIGHT: (C)2011,JPO&INPIT