ELEMENT PROVIDED WITH FIBRIN LAYER, AND PREPARATION AND USE THEREOF

PROBLEM TO BE SOLVED: To solve a fault of affecting cell attachment in the case of lacking homogeneity or uniformity of support pores with respect to an element including a fibrin-based layer. SOLUTION: The element 1 including a layer 4 based on fibrin- or fibrinogen-containing material as shown in...

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Bibliographische Detailangaben
Hauptverfasser: TASIAUX NICOLE, VERMEULEN PIERRE, BELOT NATHALIE, DELMOTTE YVES
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To solve a fault of affecting cell attachment in the case of lacking homogeneity or uniformity of support pores with respect to an element including a fibrin-based layer. SOLUTION: The element 1 including a layer 4 based on fibrin- or fibrinogen-containing material as shown in Fig.1 includes (a) a hydrophobic or substantially hydrophobic support, which has a porous part with a thickness of 0.1-5 mm, and whose pores, extending across its thickness have a node spacing of 5-100 μm, one face of the porous part being treated with a compound based on fibrin and/or fibrinogen-containing material, and (b) a fibrin-based layer covering the treated surface 3 of the support 2, characterized in that the fibrin-based layer is substantially uniform and homogeneous on the treated surface and that the fibrin layer 4 and at least the face of the support in contact with the fibrin layer are substantially free of fibrinogen. COPYRIGHT: (C)2011,JPO&INPIT