LYOPHILIZATES HAVING IMPROVED RECONSTITUTABILITY

PROBLEM TO BE SOLVED: To provide lyophilizates having an improved dissolution rate and reconstitutability, a process for their preparation, and reconstitution in a particle-free manner. SOLUTION: Corresponding solutions already filled for lyophilization, which have, if necessary, previously been war...

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Bibliographische Detailangaben
Hauptverfasser:	KURZ THEKLA, KARNATZ ARND, HESSE BRIGITTE, KRUEGER LUDWIG
Format:	Patent
Sprache:	eng
Schlagworte:	BABY COMFORTERS BLASTING CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY DEVICES FOR RECEIVING SPITTLE DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS DRYING DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM HEATING HUMAN NECESSITIES HYGIENE LIGHTING MECHANICAL ENGINEERING MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS WEAPONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide lyophilizates having an improved dissolution rate and reconstitutability, a process for their preparation, and reconstitution in a particle-free manner. SOLUTION: Corresponding solutions already filled for lyophilization, which have, if necessary, previously been warmed in order to accelerate dissolution of the substance, filtered-optionally sterile-filtered-and filled, are rewarmed to from 30°C to 95°C directly in the vials in the freeze drier, and the freezing phase is then carried out rapidly from this elevated temperature to the desired low freeze-drying temperature. COPYRIGHT: (C)2011,JPO&INPIT