STRUCTURAL CAROTENOID ANALOGUE FOR INHIBITION AND AMELIORATION OF DISEASE

PROBLEM TO BE SOLVED: To provide synthesis and use of a structural carotenoid analogue for inhibition and amelioration of a disease. SOLUTION: A pharmaceutical composition contains a compound having a structure of the formula and one or more carriers allowed of being formulated. Wherein, each of Ys...

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Hauptverfasser: WATUMULL DAVID G, NADOLSKI GEOFF, LOCKWOOD SAMUEL FOURNIER, O'MALLEY SEAN, JACKSON HENRY, HIX LAURA M
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide synthesis and use of a structural carotenoid analogue for inhibition and amelioration of a disease. SOLUTION: A pharmaceutical composition contains a compound having a structure of the formula and one or more carriers allowed of being formulated. Wherein, each of Ys is independently O or H2, each of Rs is independently -alkylene-NR23+, -alkylene-NR22, -alkylene-CO2, -CH(NH2)CH2CH2CH2CH2NH2, or -CH(NH3)+CH2CH2CH2CH2NH3+, and each of R2s is independently H, alkyl or aryl. COPYRIGHT: (C)2011,JPO&INPIT