MACROCYCLIC CARBOXYLIC ACID AND ACYLSULFONAMIDE AS INHIBITOR OF HCV REPLICATION

PROBLEM TO BE SOLVED: To provide a compound for treating hepatitis C virus (HCV) infection, its synthesizing method, its composition and a treating method using it. SOLUTION: There are provided compounds of general formulas I-IX as well as compositions including pharmaceutical compositions containin...

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Hauptverfasser:	JIANG YUTONG, BLATT LAWRENCE M, JOSEY JOHN ANTHONY, STENGEL PETER JOHN, MADDURU MACHENDER R, CONDROSKI KEVIN RONALD, WENGLOWSKY STEVEN MARK, WOODARD BENJAMIN T, DOHERTY GEORGE ANDREW, ANDREWS STEVEN WADE, KENNEDY APRIL LAYNE
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP
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Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a compound for treating hepatitis C virus (HCV) infection, its synthesizing method, its composition and a treating method using it. SOLUTION: There are provided compounds of general formulas I-IX as well as compositions including pharmaceutical compositions containing a subject compound. There are further provided treatment methods including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of the subject compound or composition. COPYRIGHT: (C)2011,JPO&INPIT