AROMATIC DERIVATIVE AS HIV ASPARTYL PROTEASE INHIBITOR

PROBLEM TO BE SOLVED: To provide a new kind of compounds, and derivatives thereof permissible as pharmaceuticals. SOLUTION: There are provided HIV aspartyl protease inhibitors of the formula (I) and, when the compound of formula (I) contains an amino group, pharmaceutically acceptable ammonium salts...

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Hauptverfasser: PERRON VALERIE, LAVALLEE JEAN-FRANCOIS, LEBERRE NICOLAS, STRANIX BRENT RICHARD
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creator PERRON VALERIE
LAVALLEE JEAN-FRANCOIS
LEBERRE NICOLAS
STRANIX BRENT RICHARD
description PROBLEM TO BE SOLVED: To provide a new kind of compounds, and derivatives thereof permissible as pharmaceuticals. SOLUTION: There are provided HIV aspartyl protease inhibitors of the formula (I) and, when the compound of formula (I) contains an amino group, pharmaceutically acceptable ammonium salts thereof, (wherein n is 3 or 4; R1may be, for example, iso-butyl; X and Y are same or different, and may be, for example, NH2and F; and R2and R3are as specifically defined herein). COPYRIGHT: (C)2010,JPO&INPIT
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title AROMATIC DERIVATIVE AS HIV ASPARTYL PROTEASE INHIBITOR
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