PHARMACEUTICAL FOR TREATING HEPATOMA

PROBLEM TO BE SOLVED: To provide a specific polypeptide capable of inhibiting growth of hepatoma. SOLUTION: There is provided an agent for treatment of hepatoma and containing bombesin antagonist peptides or their pharmaceutically permissible acid or salt. Specific examples of the bombesin antagonis...

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Hauptverfasser: SHALLY ANDREW V, SZEPESHAZI KAROLY, CAI REN-ZHI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a specific polypeptide capable of inhibiting growth of hepatoma. SOLUTION: There is provided an agent for treatment of hepatoma and containing bombesin antagonist peptides or their pharmaceutically permissible acid or salt. Specific examples of the bombesin antagonist peptides are D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-ψ-Tac-NH2, D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-ψ-MTac-NH2, Ac-D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-ψ-Tac-NH2, and D-Trp-Gln-Trp-Ala-Val-Gly-His-Leu-ψ-Tac-NH2. COPYRIGHT: (C)2010,JPO&INPIT