CHIRAL SEPARATION OF PHARMACEUTICAL COMPOUND WITH CHARGED CYCLODEXTRINS USING CAPILLARY ELECTROPHORESIS

PROBLEM TO BE SOLVED: To provide a series of novel charged cyclodextrins used for dividing (analyzing) a wide variety of chiral compounds by capillary electrophoresis. SOLUTION: The charged cyclodextrins is selected from the group consisting of (a) α-cyclodextrin, (b) β-cyclodextrin having at least...

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Hauptverfasser: SHEN GENE G Y, EVANGELISTA RAMON A, CHEN FU-TAI A, OH CHAN S
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a series of novel charged cyclodextrins used for dividing (analyzing) a wide variety of chiral compounds by capillary electrophoresis. SOLUTION: The charged cyclodextrins is selected from the group consisting of (a) α-cyclodextrin, (b) β-cyclodextrin having at least about 12 modified hydroxyl groups, and (c) γ-cyclodextrin, and includes at least one qualification of secondary hydroxyl. COPYRIGHT: (C)2010,JPO&INPIT