PREMIX DRUG PRODUCT OF EDARAVONE

PROBLEM TO BE SOLVED: To provide a premix drug product of edaravone excellent in moldability and storage stability. SOLUTION: The premix drug product of the edaravone is formed of a multilayer film or multilayer sheet including a barrier layer with a thickness of 10 to 80 μm containing a cyclic poly...

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Bibliographische Detailangaben
Hauptverfasser:	YAGO SEIJI, SAKAGUCHI ITARU, FUKUSHIMA KIYOKO
Format:	Patent
Sprache:	eng
Schlagworte:	BABY COMFORTERS CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY DEVICES FOR RECEIVING SPITTLE DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a premix drug product of edaravone excellent in moldability and storage stability. SOLUTION: The premix drug product of the edaravone is formed of a multilayer film or multilayer sheet including a barrier layer with a thickness of 10 to 80 μm containing a cyclic polyolefin resin having a glass transition point of 70 to 110°C as a main component and a seal layer of a thickness of 5 to 80 μm arranged adjacent to the barrier layer and containing a polypropylene-based resin as a main component, wherein the seal layer forms the innermost layer, an aqueous drug product including the edaravone is accommodated in a plastic container having a seal portion sealed by seal layers facing each other, and the premix drug product of the edaravone is constituted by subjecting the same to high pressure steam sterilization in a hermetically sealed condition. COPYRIGHT: (C)2010,JPO&INPIT