INHIBITING RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREA

PROBLEM TO BE SOLVED: To provide an isooxazolyl urea compound having an activity of inhibiting RAF kinase, useful in treating solid cancer, for example a cancerous tumor [such as a cancerous tumor of a lung, spleen, thyroid, bladder, or colon, or a disease of bone marrow (bone marrow leukemia for ex...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	PAULSEN HOLGER, LEE WENDY, KHIRE UDAY, RIEDL BERND, SMITH ROGER A, WOOD JILL E, REDMAN ANIKO, LOWINGER TIMOTHY BRUNO, DUMAS JACQUES, HATOUM-MOKDAD HOLIA, JOHNSON JEFFREY, SCOTT WILLIAM J
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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