SYSTEM FOR MANUFACTURING CONTROLLED RELEASE DOSAGE FORM, SUCH AS ZERO-ORDER RELEASE PROFILE DOSAGE FORM MANUFACTURED BY THREE-DIMENSIONAL PRINTING

PROBLEM TO BE SOLVED: To provide a dosage form which can provide zero-order release and a generally optional required release profile. SOLUTION: The dosage form includes the innermost region and one or more other regions, each having respective local concentration of at least one active pharmaceutic...

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Hauptverfasser: MATERNA PETER A, PRYCE LEWIS WENDY E, CHARLES WILLIAM ROWE, CIMA MICHAEL J
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a dosage form which can provide zero-order release and a generally optional required release profile. SOLUTION: The dosage form includes the innermost region and one or more other regions, each having respective local concentration of at least one active pharmaceutical ingredient. Here, each of the other regions completely surrounds the innermost region and all other regions arranged inside thereof; and has at least one active pharmaceutical ingredient in an optional contiguous region with respective local concentration different from those each of the other regions. COPYRIGHT: (C)2010,JPO&INPIT