AEROSOL DRUG FORMULATION CONTAINING POLYGLYCOLYZED GLYCERIDE

PROBLEM TO BE SOLVED: To provide aerosol delivery drug formulations miscible with a non-chlorofluorocarbon propellent, to provide, especially, as for an excipient useful in them, an inhalable formulation containing polyglycolyzed glyceride, and to provide a production method. SOLUTION: A pharmaceuti...

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Bibliographische Detailangaben
Hauptverfasser: FU LU MOU-YING, ADJEI AKWETE L, GUPTA PRAMOD K
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide aerosol delivery drug formulations miscible with a non-chlorofluorocarbon propellent, to provide, especially, as for an excipient useful in them, an inhalable formulation containing polyglycolyzed glyceride, and to provide a production method. SOLUTION: A pharmaceutical composition for aerosol delivery comprises (a) a medicament, (b) a non-chlorofluorocarbon propellent, and (c) the polyglycolyzed glyceride or a pharmaceutically acceptable salt thereof. In the method for producing such composition, undesired coagulation of the drug is prevented without using any surfactant, protective colloid, or cosolvent. COPYRIGHT: (C)2010,JPO&INPIT