IDENTIFICATION OF GENE CAUSING MOUSE SCURFY PHENOTYPE AND HUMAN ORTHOLOG OF THE GENE

PROBLEM TO BE SOLVED: To provide an isolated nucleic acid molecule encoding Fkhsf, as well as mutant forms of the nucleic acid molecule. SOLUTION: The isolated nucleic acid molecule encoding Fkhsf, as well as mutant forms of the nucleic acid molecule, are provided. Expression vectors suitable for ex...

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Hauptverfasser: RAMSDELL FRED, BRUNKOW MARY E, HJERRILD KATHRYN A, JEFFERY ERIC W
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide an isolated nucleic acid molecule encoding Fkhsf, as well as mutant forms of the nucleic acid molecule. SOLUTION: The isolated nucleic acid molecule encoding Fkhsf, as well as mutant forms of the nucleic acid molecule, are provided. Expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors are also provided. By use of assays based upon the nucleic acid sequences disclosed in the specification (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system. COPYRIGHT: (C)2010,JPO&INPIT