OPTICAL DETECTION METHOD OR IMAGING METHOD OF TRANSPLANTATION CELL

PROBLEM TO BE SOLVED: To provide a method capable of detecting and observing accurately with the passage of time, a position or spatial spread of only transplanted cells, and discriminating various transplanted cells, in an animal model experiment for observing the transplanted cells into a small an...

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Bibliographische Detailangaben
Hauptverfasser: SASAOKA CHINO, OKAMOTO NAOAKI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a method capable of detecting and observing accurately with the passage of time, a position or spatial spread of only transplanted cells, and discriminating various transplanted cells, in an animal model experiment for observing the transplanted cells into a small animal for the experiment. SOLUTION: The method of detecting in vivo transplantation cells transplanted into a small animal body includes the steps of: preparing cells into which gene for manifesting a tag which is part of a peptide or a protein on cell membranes of the cells as the transplantation cells; transplanting the transplantation cells into the small animal; and detecting the tag in the small animal. The tag may be detected, by administering a fluorescence-labeled antibody to the tag into the small animal and by imaging fluorescence from the antibody. COPYRIGHT: (C)2010,JPO&INPIT