BIODEGRADABLE ANIONIC POLYMER DERIVED FROM AMINO ACID L-TYROSINE

PROBLEM TO BE SOLVED: To provide a biodegradable anionic polymer derived from amino acid L-tyrosine. SOLUTION: A polycarbonate or a polyarylate with a hydrolytically labile main chain, and represented by formula (VIII), wherein R9is ≤18C alkyl, aryl or alkylaryl group having a carboxylic acid group...

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Hauptverfasser: BOLIKAL DURGADAS, ERTEL SYLVIE I, BRODE GEORGE L, KOHN JOACHIM B, GUAN SHUIYUN, KEMNITZER JOHN E
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creator BOLIKAL DURGADAS
ERTEL SYLVIE I
BRODE GEORGE L
KOHN JOACHIM B
GUAN SHUIYUN
KEMNITZER JOHN E
description PROBLEM TO BE SOLVED: To provide a biodegradable anionic polymer derived from amino acid L-tyrosine. SOLUTION: A polycarbonate or a polyarylate with a hydrolytically labile main chain, and represented by formula (VIII), wherein R9is ≤18C alkyl, aryl or alkylaryl group having a carboxylic acid group or a benzyl ester thereof as a side chain; R12is ≤18C alkyl, aryl or alkylaryl group having a pendant carboxylic acid ester group selected from ≤18C straight and branched alkyl and alkylaryl esters and ester derivatives of biologically and pharmaceutically active compounds covalently bonded to the polymer; each R7is independently ≤4C alkylene group; A is a carbonyl group or a dicarboxylic acid residue; k is between about 5 and about 3,000; and x and f respectively independently range from zero to less than one. COPYRIGHT: (C)2010,JPO&INPIT
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subjects CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORGANIC CHEMISTRY
ORGANIC MACROMOLECULAR COMPOUNDS
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
title BIODEGRADABLE ANIONIC POLYMER DERIVED FROM AMINO ACID L-TYROSINE
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