BIODEGRADABLE ANIONIC POLYMER DERIVED FROM AMINO ACID L-TYROSINE

PROBLEM TO BE SOLVED: To provide a biodegradable anionic polymer derived from amino acid L-tyrosine. SOLUTION: A polycarbonate or a polyarylate with a hydrolytically labile main chain, and represented by formula (VIII), wherein R9is ≤18C alkyl, aryl or alkylaryl group having a carboxylic acid group...

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Hauptverfasser:	BOLIKAL DURGADAS, ERTEL SYLVIE I, BRODE GEORGE L, KOHN JOACHIM B, GUAN SHUIYUN, KEMNITZER JOHN E
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a biodegradable anionic polymer derived from amino acid L-tyrosine. SOLUTION: A polycarbonate or a polyarylate with a hydrolytically labile main chain, and represented by formula (VIII), wherein R9is ≤18C alkyl, aryl or alkylaryl group having a carboxylic acid group or a benzyl ester thereof as a side chain; R12is ≤18C alkyl, aryl or alkylaryl group having a pendant carboxylic acid ester group selected from ≤18C straight and branched alkyl and alkylaryl esters and ester derivatives of biologically and pharmaceutically active compounds covalently bonded to the polymer; each R7is independently ≤4C alkylene group; A is a carbonyl group or a dicarboxylic acid residue; k is between about 5 and about 3,000; and x and f respectively independently range from zero to less than one. COPYRIGHT: (C)2010,JPO&INPIT